Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230970 | 0.92 | NR1H4 (0.31) | — | |
| SCHEMBL19230677 | 0.88 | FAAH (0.35) | TAS1R3TAS1R1TAS1R2RAB9AFAAH | |
| SCHEMBL19230598 | 0.85 | FAAH (0.34) | FAAH | |
| SCHEMBL19230657 | 0.80 | SLC8A1 (0.36) | — | |
| SCHEMBL19230593 | 0.80 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2DRD2DRD4 | |
| SCHEMBL19230696 | 0.79 | ITGB3 (0.39) | — | |
| SCHEMBL19230520 | 0.79 | PPARG (0.33) | — | |
| SCHEMBL19230654 | 0.79 | ITGB3 (0.33) | — | |
| SCHEMBL19230813 | 0.79 | FAAH (0.35) | TAS1R3TAS1R1TAS1R2RAB9AFAAH | |
| SCHEMBL19230784 | 0.78 | SLC8A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |