Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25582979 | 0.82 | TSHR (0.53) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL3496640 | 0.82 | ALDH1A1 (0.68) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL25650882 | 0.78 | ALDH1A1 (0.44) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL26461278 | 0.77 | TSHR (0.52) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL19232186 | 0.76 | KMT2A (0.39) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL23522306 | 0.76 | ALDH1A1 (0.51) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL20018349 | 0.76 | TSHR (0.55) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL27727625 | 0.75 | TSHR (0.59) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL25583054 | 0.75 | TSHR (0.48) | TSHRALDH1A1KMT2APOLBMAPT | |
| SCHEMBL9843494 | 0.73 | ALDH1A1 (0.50) | TSHRALDH1A1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030834-B2 | Methods of synthesizing 4-valyloxybutyric acid | XWPharma Ltd. (KY) | 2024-07-09 | — | — | US | disclosed |
| WO-2024005461-A1 | NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR | 주식회사 트리오어 | 2024-01-04 | — | — | WO | disclosed |
| WO-2024005460-A1 | COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME | 주식회사 트리오어 | 2024-01-04 | — | — | WO | disclosed |
| US-20230357130-A1 | METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID | XWPharma Ltd. (KY) | 2023-11-09 | — | — | US | disclosed |
| WO-2023196307-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-11746081-B2 | Methods of synthesizing 4-valyloxybutyric acid | XWPharma Ltd. (KY) | 2023-09-05 | — | — | US | disclosed |
| WO-2023081230-A1 | NOVEL AURISTATIN ANALOGS AND IMMUNOCONJUGATES THEREOF | ADCENTRX THERAPEUTICS INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021127461-A1 | METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID | XW LABORATORIES LIMITED (CN) | 2021-06-24 | — | — | WO | disclosed |
| WO-2017134548-A1 | PROCESS FOR THE PREPARATION OF LEDIPASVIR AND INTERMEDIATES THEREOF | LUPIN LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030834-B2 | Methods of synthesizing 4-valyloxybutyric acid | GABBR1, GABBR2, GABRB3 | TSHR 3405/4885ALDH1A1 2199/4885KMT2A 2039/4885 |
| US-20230357130-A1 | METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID | GABBR1, GABBR2, GABRB3 | TSHR 3405/4885ALDH1A1 2199/4885KMT2A 2039/4885 |
| US-11746081-B2 | Methods of synthesizing 4-valyloxybutyric acid | GABBR1, GABBR2, GABRB3 | TSHR 3405/4885ALDH1A1 2199/4885KMT2A 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.