Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19232192 | 0.76 | TSHR (0.50) | KMT2ATSHRALDH1A1MAPTPOLB | |
| SCHEMBL19309377 | 0.74 | KMT2A (0.53) | KMT2AMGLLTSHRALDH1A1MAPT | |
| SCHEMBL133554 | 0.74 | KMT2A (0.53) | KMT2AMGLLTSHRALDH1A1MAPT | |
| SCHEMBL8641759 | 0.74 | TAS1R3 (0.33) | KMT2AMGLLTSHRALDH1A1SLC1A2 | |
| SCHEMBL6948244 | 0.74 | PREP (0.43) | MGLLALDH1A1MAPTHTTLMNA | |
| SCHEMBL13770429 | 0.73 | MGLL (0.31) | MGLLSLC1A2 | |
| SCHEMBL25993237 | 0.73 | MGLL (0.31) | MGLLSLC1A2 | |
| SCHEMBL4425151 | 0.73 | CTSB (0.53) | KMT2AMEN1RAB9ACYP2D6 | |
| SCHEMBL10357140 | 0.73 | CTSB (0.53) | KMT2AMEN1RAB9ACYP2D6 | |
| SCHEMBL4039888 | 0.73 | CTSB (0.53) | KMT2AMEN1RAB9ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134548-A1 | PROCESS FOR THE PREPARATION OF LEDIPASVIR AND INTERMEDIATES THEREOF | LUPIN LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |