Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17170376 | 0.82 | POLB (0.44) | POLBNAMPTHTTNPC1RAB9A | |
| SCHEMBL19233211 | 0.81 | TRPV1 (0.46) | POLBNAMPTHTTNPC1RAB9A | |
| SCHEMBL19465881 | 0.78 | POLB (0.38) | POLBLMNAALDH1A1 | |
| SCHEMBL23870191 | 0.77 | AOC3 (0.40) | POLBHTTNPC1RAB9ALMNA | |
| SCHEMBL20031971 | 0.70 | HDAC3 (0.45) | POLBNPC1RAB9AHDAC1MAOB | |
| SCHEMBL18646287 | 0.70 | POLB (0.38) | POLBNAMPTHTTNPC1RAB9A | |
| SCHEMBL13901420 | 0.69 | POLB (0.54) | POLBNPC1RAB9AATM | |
| SCHEMBL18697940 | 0.69 | TRPV1 (0.42) | POLBNAMPTHTTTRPV1 | |
| SCHEMBL19299882 | 0.68 | PKM (0.35) | HTTATMALDH1A1 | |
| SCHEMBL19872673 | 0.68 | NPC1 (0.51) | POLBHTTNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017042380-A1 | NOVEL 5-AMINO-2-THIOIMIDAZOLE COMPOUNDS AND THEIR USE | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2017-03-16 | — | — | WO | disclosed |