SCHEMBL23870191

SCHEMBL23870191

CC(C)=CCOc1ccc(C(=O)NC(C)(C)CCOC(C)(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AOC3 Q16853 2/20 0.40
▸ MAOB P27338 1/20 0.40
▸ NDUFS8 O00217 1/20 0.39
▸ COXFA4 O00483 1/20 0.39
▸ NDUFAB1 O14561 1/20 0.39
▸ NDUFA1 O15239 1/20 0.39
▸ NDUFS4 O43181 1/20 0.39
▸ NDUFB5 O43674 1/20 0.39
▸ NDUFB3 O43676 1/20 0.39
▸ NDUFC1 O43677 1/20 0.39
▸ NDUFA2 O43678 1/20 0.39
▸ NDUFS5 O43920 1/20 0.39
▸ NDUFS7 O75251 1/20 0.39
▸ NDUFS2 O75306 1/20 0.39
▸ NDUFS6 O75380 1/20 0.39
▸ NDUFB1 O75438 1/20 0.39
▸ NDUFS3 O75489 1/20 0.39
▸ NDUFB6 O95139 1/20 0.39
▸ NDUFA3 O95167 1/20 0.39
▸ NDUFB4 O95168 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23870165 0.81 NDUFS8 (0.41) AOC3MAOBNDUFS8COXFA4NDUFAB1
SCHEMBL19872673 0.79 NPC1 (0.51) PLK1MAPTLMNAADRB2ADRB1
SCHEMBL18646429 0.77 POLB (0.40) AOC3MAOBLMNAHTTNPC1
SCHEMBL28601702 0.75 CA1 (0.57) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
SCHEMBL19233211 0.75 TRPV1 (0.46) HTTNPC1POLBRAB9A
SCHEMBL19465881 0.73 POLB (0.38) MEN1LMNAHPGDBLMKMT2A
SCHEMBL22192216 0.72 NPC1 (0.64) MAPTMEN1LMNAKMT2AHTT
SCHEMBL3895936 0.71 L3MBTL1 (0.61) MAOBMAPTLMNAHPGDHTT
SCHEMBL2313483 0.70 MAPT (0.64) MAPTMEN1LMNAKMT2AHTT
Valencic Acid SCHEMBL3316632 0.70 PKM (0.53) MAPTMEN1NR1I2LMNAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210301078-A1 COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-09-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210301078-A1 COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS RNGTT, NSUN2, POLN AOC3 3695/4885MAOB 4007/4885NDUFS8 3300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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