Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698021 | 0.86 | TRPV1 (0.46) | TRPV1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL22040078 | 0.81 | TRPV1 (0.54) | TRPV1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL19233211 | 0.81 | TRPV1 (0.46) | TRPV1NAMPTHTTRAB9A | |
| SCHEMBL19478063 | 0.78 | LMNA (0.40) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16738817 | 0.77 | TRPV1 (0.53) | TRPV1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL2590735 | 0.72 | TRPV1 (0.50) | TRPV1NAMPTMLYCD | |
| SCHEMBL25893618 | 0.72 | TRPV1 (0.45) | TRPV1ALDH1A1RAB9AMLYCD | |
| SCHEMBL4688446 | 0.71 | DGAT1 (0.47) | TRPV1ALDH1A1LMNARAB9A | |
| SCHEMBL1490749 | 0.71 | HPGD (0.62) | TRPV1NAMPTALDH1A1MEN1RAB9A | |
| SCHEMBL29950607 | 0.71 | KDM4E (0.55) | TRPV1ALDH1A1LMNAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323628-B1 | CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INST OF TECHN (US) | 2022-04-13 | — | — | EP | disclosed |
| US-20210283258-A1 | TARGETED NANOPARTICLES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-09-16 | — | — | US | disclosed |
| EP-3714903-A1 | NANOPARTICLES STABILIZED WITH NIITROPHENYLBORONIC ACID COMPOSITIONS | California Institute of Technology (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3513812-B1 | NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS | CALIFORNIA INST OF TECHN (US) | 2020-07-15 | — | — | EP | disclosed |
| US-20190314520-A1 | Carrier Nanoparticles And Related Compositions, Methods And Systems | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-10-17 | — | — | US | disclosed |
| US-10342879-B2 | Carrier nanoparticles and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-09 | — | — | US | disclosed |
| US-20190000990-A1 | Carrier Nanoparticles And Related Compositions, Methods And Systems | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-01-03 | — | — | US | disclosed |
| US-9913911-B2 | Carrier nanoparticles and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-03-13 | — | — | US | disclosed |
| US-20170080099-A1 | CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342879-B2 | Carrier nanoparticles and related compositions, methods and systems | CA13, CA12, CLTA | TRPV1 3659/4885PRSS1 2463/4885CTSG 837/4885 |
| US-20190314520-A1 | Carrier Nanoparticles And Related Compositions, Methods And Systems | CA13, CA12, CLTA | TRPV1 3659/4885PRSS1 2463/4885CTSG 837/4885 |
| US-20210283258-A1 | TARGETED NANOPARTICLES | CLTB, NBAS, NAPA | TRPV1 3494/4885PRSS1 1995/4885CTSG 2325/4885 |
| US-20190000990-A1 | Carrier Nanoparticles And Related Compositions, Methods And Systems | CA13, CA12, CLTA | TRPV1 3659/4885PRSS1 2463/4885CTSG 837/4885 |
| US-20170080099-A1 | CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CA13, CA12, CLTA | TRPV1 3659/4885PRSS1 2463/4885CTSG 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.