Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CFD | P00746 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233806 | 0.85 | CREBBP (0.47) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL19234267 | 0.81 | KMT2A (0.40) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL29195128 | 0.75 | KMT2A (0.38) | KMT2AMEN1POLBCFDKDM4E | |
| SCHEMBL25827703 | 0.72 | IMPDH2 (0.36) | KMT2AMEN1STAT3POLBALDH1A1 | |
| SCHEMBL12481379 | 0.72 | KDM4E (0.41) | KMT2AMEN1POLBCFDKDM4E | |
| SCHEMBL8530588 | 0.72 | KDM4E (0.41) | KMT2AMEN1POLBCFDKDM4E | |
| SCHEMBL21725009 | 0.70 | KMT2A (0.49) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL8530590 | 0.70 | TFPI2 (0.49) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL12479862 | 0.69 | ALDH1A1 (0.48) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL19159440 | 0.68 | CFD (0.47) | KMT2AMEN1POLBCFDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661433-B1 | INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) | NOVARTIS AG (CH) | 2017-08-16 | — | — | EP | disclosed |