SCHEMBL19234644

CSC(=O)NC[C@H](NC(=O)[C@@H](N)Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](Cc1ccc(C(N)=O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](Cc1ccc(O)cc1)C(N)=O)C(C)O

nearest known ligand 0.45

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	5/20	0.45

▸	NPY4R	P50391	10/20	0.43

▸	NPY5R	Q15761	7/20	0.43

▸	NPY1R	P25929	7/20	0.43

▸	NPY2R	P49146	4/20	0.43

▸	OPRM1	P35372	2/20	0.41

▸	OPRD1	P41143	2/20	0.41

▸	OPRK1	P41145	2/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20715848	0.92	NPY4R (0.46)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL20715939	0.87	KISS1R (0.45)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL20715753	0.87	KISS1R (0.45)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL24340468	0.85	KISS1R (0.46)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL24340680	0.85	KISS1R (0.46)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL24340682	0.80	NPY4R (0.44)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL29511585	0.80	NPY4R (0.53)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL24324975	0.78	NPY4R (0.45)	KISS1RNPY4RNPY5RNPY1RNPY2R
SCHEMBL13224352	0.78	FURIN (0.47)	NPY4RNPY5RNPY1RNPY2ROPRK1
SCHEMBL29531633	0.78	OPRD1 (0.50)	KISS1RNPY4RNPY1RNPY2ROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017136943-A1	SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME	CDRD VENTURES INC. (CA)	2017-08-17	—	—	WO	disclosed