Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.60 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13258710 | 0.87 | LTA4H (0.62) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL20715656 | 0.86 | LTA4H (0.58) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL26464130 | 0.85 | LTA4H (0.60) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL17424310 | 0.83 | SPHK1 (0.51) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL23656874 | 0.83 | LTA4H (0.43) | LTA4HSPHK1SPHK2MMP2TERT | |
| SCHEMBL17637516 | 0.82 | LTA4H (0.56) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL17661962 | 0.82 | LTA4H (0.56) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL19234501 | 0.82 | SPHK1 (0.53) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL13820164 | 0.82 | LTA4H (0.70) | LTA4HSPHK1MMP2MMP9TERT | |
| SCHEMBL370590 | 0.82 | CRHBP (0.59) | SPHK1SPHK2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136943-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2017-08-17 | — | — | WO | disclosed |