SCHEMBL1923563

SCHEMBL1923563

Fc1ccc(Nc2nc(NCc3ccncc3)nc(Nc3ccc(F)cc3)n2)cc1

nearest known ligand 0.97

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 20/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1924273 0.83 KCNH3 (1.00) KCNH3
SCHEMBL1923875 0.83 KCNH3 (0.71) KCNH3
SCHEMBL5015629 0.83 KCNH3 (0.69) KCNH3
SCHEMBL5998625 0.83 KCNH3 (0.68) KCNH3
SCHEMBL1923791 0.82 KCNH3 (0.97) KCNH3
SCHEMBL1923916 0.82 KCNH3 (0.97) KCNH3
Hydrochloric Acid SCHEMBL3413936 0.81 KCNH3 (1.00) KCNH3
SCHEMBL1282204 0.79 KCNH3 (1.00) KCNH3
SCHEMBL5023655 0.79 KCNH3 (0.68) KCNH3
SCHEMBL1281719 0.78 KCNH3 (0.97) KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479397-B1 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE ASTELLAS PHARMA INC (JP) 2011-06-08 EP claimed