Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 12/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923699 | 0.86 | KCNH3 (0.73) | KCNH3LTA4HALDH1A1 | |
| SCHEMBL10371775 | 0.86 | LTA4H (0.72) | MEN1MAPTPABPC1KMT2APOLB | |
| SCHEMBL1923563 | 0.83 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL5015629 | 0.82 | KCNH3 (0.69) | KCNH3 | |
| SCHEMBL5023655 | 0.81 | KCNH3 (0.68) | KCNH3 | |
| SCHEMBL30784989 | 0.80 | PKM (0.67) | KCNH3MEN1MAPTKMT2ALTA4H | |
| SCHEMBL1923791 | 0.78 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL25638651 | 0.78 | LTA4H (0.60) | MEN1MAPTPABPC1KMT2APOLB | |
| SCHEMBL22546801 | 0.77 | CYP3A4 (0.63) | MEN1MAPTPABPC1KMT2APOLB | |
| SCHEMBL1280999 | 0.77 | KCNH3 (1.00) | KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |