SCHEMBL5023655

SCHEMBL5023655

Fc1ccc(Nc2nc(NCc3ccnnc3)nc(Nc3ccccc3)n2)cc1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5015629 0.95 KCNH3 (0.69) KCNH3
SCHEMBL5017676 0.85 KCNH3 (0.69) KCNH3
SCHEMBL1923791 0.83 KCNH3 (0.97) KCNH3
SCHEMBL1923875 0.81 KCNH3 (0.71) KCNH3
SCHEMBL1281719 0.81 KCNH3 (0.97) KCNH3
Hydrochloric Acid SCHEMBL541197 0.80 KCNH3 (1.00) KCNH3
SCHEMBL1923563 0.79 KCNH3 (0.97) KCNH3
SCHEMBL5023658 0.79 KCNH3 (0.76) KCNH3
SCHEMBL535908 0.78 KCNH3 (1.00) KCNH3
SCHEMBL5015093 0.78 KCNH3 (0.74) KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375222-B2 2,4,6-Triamino-1,3,5-triazine derivative ASTELLAS PHARMA INC. (JP) 2008-05-20 US claimed