Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.73 |
| ▸ | LTA4H | P09960 | 1/20 | 0.73 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784989 | 0.93 | PKM (0.67) | KCNH3LTA4HGPR84PKMRAD52 | |
| SCHEMBL1923875 | 0.86 | KCNH3 (0.71) | KCNH3LTA4HALDH1A1 | |
| SCHEMBL523753 | 0.84 | LTA4H (1.00) | LTA4HGPR84ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL30642394 | 0.84 | LTA4H (1.00) | LTA4HGPR84ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL1924273 | 0.83 | KCNH3 (1.00) | KCNH3RECQLMCL1 | |
| SCHEMBL5605047 | 0.79 | LTA4H (0.82) | LTA4HALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4805011 | 0.78 | LTA4H (0.79) | KCNH3LTA4HALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL1310247 | 0.77 | PKM (0.76) | LTA4HGPR84PKMRAD52ALDH1A1 | |
| SCHEMBL30784987 | 0.77 | MEN1 (0.62) | LTA4HGPR84PKMRAD52ALDH1A1 | |
| SCHEMBL30784980 | 0.77 | MEN1 (0.62) | LTA4HGPR84PKMRAD52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |