Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 14/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282204 | 0.90 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL1923864 | 0.85 | KCNH3 (0.90) | KCNH3 | |
| SCHEMBL1282182 | 0.81 | KCNH3 (1.00) | KCNH3ALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL1923730 | 0.77 | KCNH3 (0.98) | KCNH3ALDH1A1MAPTNPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL3411999 | 0.76 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL5017676 | 0.75 | KCNH3 (0.69) | KCNH3ALDH1A1MAPTMEN1GAA | |
| SCHEMBL1924158 | 0.73 | KCNH3 (0.71) | KCNH3 | |
| SCHEMBL11812041 | 0.71 | MAPT (0.81) | KCNH3ALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL1923563 | 0.71 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL1391546 | 0.71 | PDE4B (0.70) | KCNH3ALDH1A1MAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |