Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 16/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015629 | 0.90 | KCNH3 (0.69) | KCNH3 | |
| SCHEMBL5023655 | 0.85 | KCNH3 (0.68) | KCNH3 | |
| SCHEMBL1923730 | 0.82 | KCNH3 (0.98) | KCNH3ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL3411999 | 0.81 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL1282182 | 0.79 | KCNH3 (1.00) | KCNH3ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL1923780 | 0.75 | KCNH3 (0.81) | KCNH3ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL1923563 | 0.75 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL1924396 | 0.74 | KCNH3 (0.83) | KCNH3ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL1923561 | 0.74 | KCNH3 (0.98) | KCNH3 | |
| SCHEMBL1923875 | 0.74 | KCNH3 (0.71) | KCNH3ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |