Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 8/20 | 0.81 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL540872 | 0.99 | KCNH3 (0.82) | KCNH3RAB9ANPC1JAK2SMN1; SMN2 | |
| SCHEMBL540938 | 0.90 | KCNH3 (0.91) | KCNH3RAB9ANPC1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL540609 | 0.90 | KCNH3 (0.82) | KCNH3SMN1; SMN2FFAR1KDM4E | |
| Hydrochloric Acid SCHEMBL1281689 | 0.89 | KCNH3 (1.00) | KCNH3RAB9ANPC1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL540943 | 0.84 | KCNH3 (0.73) | KCNH3RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1924291 | 0.83 | KCNH3 (0.84) | KCNH3RAB9ANPC1HTTMEN1 | |
| SCHEMBL5017701 | 0.76 | KCNH3 (0.62) | KCNH3RAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL1924293 | 0.74 | KCNH3 (0.98) | KCNH3 | |
| Hydrochloric Acid SCHEMBL3410329 | 0.74 | KCNH3 (1.00) | KCNH3 | |
| SCHEMBL8612276 | 0.70 | RAB9A (0.55) | RAB9ANPC1JAK2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |