Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540938 | 0.77 | KCNH3 (0.91) | KCNH3MAPTKMT2AMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1281689 | 0.76 | KCNH3 (1.00) | KCNH3MAPTKDM4EKMT2AMAPK1 | |
| SCHEMBL1923896 | 0.76 | KCNH3 (0.81) | KCNH3MAPTKDM4EKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL540872 | 0.75 | KCNH3 (0.82) | KCNH3MAPTKDM4EKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL540609 | 0.75 | KCNH3 (0.82) | KCNH3KDM4ESMN1; SMN2BLMTDP1 | |
| SCHEMBL2453813 | 0.70 | GAA (0.73) | KCNH3MAPTKDM4EKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL540943 | 0.70 | KCNH3 (0.73) | KCNH3MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL1924291 | 0.69 | KCNH3 (0.84) | KCNH3MAPTKDM4EKMT2AMAPK1 | |
| SCHEMBL21530413 | 0.68 | NPC1 (0.54) | MAPTKDM4EKMT2AMAPK1XBP1 | |
| SCHEMBL5014129 | 0.68 | KCNH3 (0.97) | KCNH3MAPTKDM4EKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |