SCHEMBL19239106

SCHEMBL19239106

c1ccc(N(c2ccccc2)c2ccc3sc4cc(N(c5ccccc5)c5ccc6oc7ccccc7c6c5)c5ccccc5c4c3c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AHR P35869 1/20 0.32
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19239189 1.00 KDM4E (0.35) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL20201284 0.97 NPC1 (0.33) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL20201283 0.94 AHR (0.34) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL25885167 0.94 NPC1 (0.35) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL15852580 0.93 KDM4E (0.32) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL24000011 0.90 MAPT (0.38) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL25884855 0.90 MAPT (0.38) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL15852654 0.90 NPC1 (0.33) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL22505822 0.89 NPC1 (0.35) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL15852566 0.89 KDM4E (0.33) KDM4EALDH1A1MAPTCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210098706-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-04-01 US disclosed
US-10651391-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-05-12 US disclosed
US-20190245148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2019-08-08 US disclosed
US-10319915-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-06-11 US disclosed
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-31 US disclosed
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-31 US disclosed
US-20170237013-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-08-17 US disclosed
US-20170237013-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210098706-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF EED, PIEZO1, TRPA1 KDM4E 958/4885MEN1 2306/4885NPC1 3065/4885
US-10319915-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof EML4, EBPL, NFE2L2 KDM4E 902/4885MEN1 1291/4885NPC1 2788/4885
US-20170237013-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EML4, EBPL, NFE2L2 KDM4E 902/4885MEN1 1291/4885NPC1 2788/4885
US-20190245148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EML4, EBPL, NFE2L2 KDM4E 902/4885MEN1 1291/4885NPC1 2788/4885
US-20180151806-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EBPL, EML4, NFE2L2 KDM4E 853/4885MEN1 1394/4885NPC1 2671/4885
US-10651391-B2 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof EML4, EBPL, NFE2L2 KDM4E 902/4885MEN1 1291/4885NPC1 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.