Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16383596 | 0.95 | ALOX5 (0.36) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL22000217 | 0.94 | ALOX5 (0.34) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL19239386 | 0.93 | TERT (0.31) | POLBLMNAMAPTTSHRHTT | |
| SCHEMBL21999500 | 0.93 | ALOX5 (0.34) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL21999477 | 0.93 | ALOX5 (0.34) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL21999495 | 0.92 | ALOX5 (0.33) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL19239385 | 0.91 | ALOX5 (0.35) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL22000222 | 0.91 | POLB (0.33) | ALOX5POLBLMNAMAPTTSHR | |
| SCHEMBL19239396 | 0.91 | LMNA (0.32) | POLBLMNAMAPTTSHRHTT | |
| SCHEMBL21999498 | 0.90 | ALOX5 (0.31) | ALOX5POLBLMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | MERCK SHARP & DOHME CORP. (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | BACE1, BACE2, APP | ALOX5 2575/4885POLB 762/4885LMNA 496/4885 |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, ETFA, TST | ALOX5 890/4885POLB 1725/4885LMNA 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.