Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831238 | 0.78 | NAAA (0.51) | TSHR | |
| SCHEMBL7652075 | 0.76 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL19123705 | 0.76 | ACHE (0.70) | ACHEALDH1A1 | |
| SCHEMBL19239816 | 0.76 | TDP1 (0.39) | ALDH1A1 | |
| SCHEMBL20469924 | 0.76 | ACHE (0.46) | ACHETSHRALDH1A1 | |
| SCHEMBL19123782 | 0.76 | ACHE (0.70) | ACHEALDH1A1 | |
| SCHEMBL19249052 | 0.75 | ACHE (0.44) | ACHETSHR | |
| SCHEMBL3819941 | 0.75 | ACHE (0.59) | ACHE | |
| SCHEMBL29612809 | 0.75 | ACHE (0.67) | ACHETSHR | |
| SCHEMBL7494523 | 0.75 | ACHE (0.67) | ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | ACHE 4607/4885TSHR 4447/4885ALDH1A1 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.