Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19123705 | 1.00 | ACHE (0.70) | ACHEEPHX2EPHX1ALDH1A1 | |
| SCHEMBL20869876 | 0.86 | ACHE (0.52) | ACHEEPHX2 | |
| SCHEMBL19123781 | 0.85 | ACHE (0.50) | ACHE | |
| SCHEMBL22930181 | 0.85 | ACHE (0.50) | ACHE | |
| SCHEMBL13700148 | 0.85 | ACHE (0.89) | ACHEEPHX2EPHX1 | |
| SCHEMBL7693663 | 0.85 | ACHE (0.89) | ACHEEPHX2EPHX1 | |
| SCHEMBL5831175 | 0.85 | ACHE (0.89) | ACHEEPHX2EPHX1 | |
| SCHEMBL7156374 | 0.85 | ACHE (0.89) | ACHEEPHX2EPHX1 | |
| SCHEMBL1416385 | 0.85 | ACHE (0.89) | ACHEEPHX2EPHX1 | |
| SCHEMBL13700154 | 0.85 | ACHE (0.89) | ACHEEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342761-B2 | Method of encapsulating a nucleic acid in a lipid nanoparticle host | NOVARTIS AG (CH) | 2019-07-09 | — | — | US | disclosed |
| US-20170196809-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196809-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | POLN, POLRMT, RNGTT | ACHE 4420/4885EPHX2 3879/4885EPHX1 2905/4885 |
| US-10342761-B2 | Method of encapsulating a nucleic acid in a lipid nanoparticle host | POLN, POLRMT, RNGTT | ACHE 4420/4885EPHX2 3879/4885EPHX1 2905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.