Sugi Predict

Sugi Predict / Compounds / SCHEMBL19243117

SCHEMBL19243117

SCHEMBL19243117

O=C1NC(O)c2ccc3c4ccc5c6ccc7c8c(ccc(c9ccc(c%10ccc1c2c%103)c4c95)c86)C(=O)N(c1ccccc1)C7=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.49
▸ ALDH1A1 P00352 6/20 0.49
▸ POLB P06746 4/20 0.49
▸ L3MBTL1 Q9Y468 3/20 0.49
▸ RECQL P46063 2/20 0.49
▸ CASP6 P55212 2/20 0.49
▸ TDP1 Q9NUW8 2/20 0.49
▸ APOBEC3A P31941 1/20 0.49
▸ APOBEC3G Q9HC16 1/20 0.49
▸ KMT2A Q03164 5/20 0.45
▸ USP2 O75604 4/20 0.45
▸ MAPT P10636 2/20 0.45
▸ HTT P42858 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ KEAP1 Q14145 2/20 0.45
▸ NFE2L2 Q16236 2/20 0.45
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ MEN1 O00255 4/20 0.42
▸ GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20132525 1.00 KDM4E (0.49) KDM4EALDH1A1POLBL3MBTL1RECQL
SCHEMBL18476614 0.83 POLB (0.62) KDM4EALDH1A1POLBL3MBTL1RECQL
SCHEMBL20017043 0.81 KDM4E (0.52) KDM4EALDH1A1POLBL3MBTL1RECQL
SCHEMBL21023279 0.81 KDM4E (0.52) KDM4EALDH1A1POLBL3MBTL1RECQL
SCHEMBL14767877 0.81 KDM4E (0.52) KDM4EALDH1A1POLBL3MBTL1RECQL
SCHEMBL19243128 0.80 PARP1 (0.39) POLBRECQLTDP1KMT2AUSP2
SCHEMBL7597209 0.80 KDM4E (0.51) KDM4EALDH1A1POLBL3MBTL1RECQL
SCHEMBL19427159 0.80 PARP1 (0.39) POLBRECQLTDP1KMT2AUSP2
SCHEMBL18116645 0.80 PARP1 (0.39) POLBRECQLTDP1KMT2AUSP2
SCHEMBL7597013 0.80 KDM4E (0.51) KDM4EALDH1A1POLBL3MBTL1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200255453-A1 ENERGY STORAGE MOLECULAR MATERIAL, CRYSTAL DIELECTRIC LAYER AND CAPACITOR CAPACITOR SCIENCES INCORPORATED 2020-08-13 — — US disclosed
US-20170283618-A1 NON-LINEAR DIELECTRIC MATERIALS AND CAPACITOR CAPACITOR SCIENCES INCORPORATED 2017-10-05 — — US disclosed
US-20170237274-A1 GRID CAPACITIVE POWER STORAGE SYSTEM CAPACITOR SCIENCES INCORPORATED (US) 2017-08-17 — — US disclosed
US-20170233528-A1 SHARP POLYMER AND CAPACITOR CAPACITOR SCIENCES INCORPORATED 2017-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255453-A1 ENERGY STORAGE MOLECULAR MATERIAL, CRYSTAL DIELECTRIC LAYER AND CAPACITOR EPCAM, PIEZO1, L1CAM KDM4E 632/4885ALDH1A1 3973/4885POLB 3981/4885
US-20170233528-A1 SHARP POLYMER AND CAPACITOR PARG, NONO, KCNN2 KDM4E 3070/4885ALDH1A1 4747/4885POLB 987/4885
US-20170283618-A1 NON-LINEAR DIELECTRIC MATERIALS AND CAPACITOR VDAC1, VDAC2, NONO KDM4E 976/4885ALDH1A1 3291/4885POLB 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.