SCHEMBL19243128

SCHEMBL19243128

O=C1NC(=O)c2ccc3c4ccc5c6ccc7c8ccc9c%10c(ccc(c%11ccc(c%12ccc(c%13ccc1c2c%133)c4c%125)c6c%117)c%108)C(=O)NC9O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 1/20 0.39
RGS12 O14924 1/20 0.39
USP2 O75604 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
CYP2C9 P11712 1/20 0.39
APEX1 P27695 1/20 0.39
CASP1 P29466 1/20 0.39
BRCA1 P38398 1/20 0.39
MTOR P42345 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
CASP7 P55210 1/20 0.39
GNAI1 P63096 1/20 0.39
HBB P68871 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19427159 1.00 PARP1 (0.39) PARP1NPSR1MEN1RGS12USP2
SCHEMBL18116645 1.00 PARP1 (0.39) PARP1NPSR1MEN1RGS12USP2
SCHEMBL18475489 0.93 PARP1 (0.42) PARP1NPSR1MEN1RGS12USP2
SCHEMBL20132525 0.80 KDM4E (0.49) MEN1USP2POLBMAPTAPEX1
SCHEMBL19243117 0.80 KDM4E (0.49) MEN1USP2POLBMAPTAPEX1
SCHEMBL29541 0.78 PARP1 (0.50) PARP1NPSR1MEN1RGS12USP2
SCHEMBL7598089 0.78 PARP1 (0.50) PARP1NPSR1MEN1RGS12USP2
SCHEMBL7601076 0.78 PARP1 (0.50) PARP1NPSR1MEN1RGS12USP2
SCHEMBL30606639 0.78 PARP1 (0.50) PARP1NPSR1MEN1RGS12USP2
SCHEMBL20223320 0.75 PARP1 (0.36) PARP1NPSR1MEN1RGS12USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200255453-A1 ENERGY STORAGE MOLECULAR MATERIAL, CRYSTAL DIELECTRIC LAYER AND CAPACITOR CAPACITOR SCIENCES INCORPORATED 2020-08-13 US disclosed
US-20170287637-A1 ELECTRO-POLARIZABLE COMPOUND AND CAPACITOR CAPACITOR SCIENCES INCORPORATED 2017-10-05 US disclosed
US-20170233528-A1 SHARP POLYMER AND CAPACITOR CAPACITOR SCIENCES INCORPORATED 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255453-A1 ENERGY STORAGE MOLECULAR MATERIAL, CRYSTAL DIELECTRIC LAYER AND CAPACITOR EPCAM, PIEZO1, L1CAM PARP1 958/4885NPSR1 4084/4885MEN1 2170/4885
US-20170233528-A1 SHARP POLYMER AND CAPACITOR PARG, NONO, KCNN2 PARP1 81/4885NPSR1 4593/4885MEN1 1862/4885
US-20170287637-A1 ELECTRO-POLARIZABLE COMPOUND AND CAPACITOR KCNJ2, KCNE1, KCNN4 PARP1 1841/4885NPSR1 3777/4885MEN1 1417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.