Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443755 | 0.89 | MAPT (0.50) | MAPTADORA2ABACE1BACE2ADRA2A | |
| SCHEMBL9494550 | 0.88 | TDP1 (0.43) | TDP1APPMAPTGAAMAOA | |
| SCHEMBL14253823 | 0.88 | APP (0.44) | TDP1APPMAPTCYP1A2ALOX12 | |
| SCHEMBL28621183 | 0.86 | PRSS1 (0.42) | TDP1APPMAPTADORA2AGAA | |
| SCHEMBL28657195 | 0.85 | PRSS1 (0.43) | TDP1APPMAPTALDH1A1 | |
| SCHEMBL11472557 | 0.84 | APP (0.42) | TDP1APPMAPTCYP1A2ALOX12 | |
| SCHEMBL21799587 | 0.82 | APP (0.41) | TDP1APPMAPTGAAMAOA | |
| SCHEMBL14594024 | 0.81 | APP (0.46) | APPMAPTCYP1A2ALOX12CYP2C9 | |
| SCHEMBL183639 | 0.81 | MAPT (0.67) | MAPTADORA2AADRA2AALOX12LMNA | |
| SCHEMBL26000374 | 0.81 | MEN1 (0.47) | MAPTADORA2ABACE1BACE2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971119-B | Heterogeneous catalyst for carbamate synthesis | 科思创知识产权两合公司 | 2023-12-08 | — | — | CN | claimed |
| US-11406964-B2 | Heterogeneous catalysts for the synthesis of carbamates | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2022-08-09 | — | — | US | claimed |
| CN-110650944-B | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | 科思创德国股份有限公司 | 2022-07-19 | — | — | CN | claimed |
| EP-3625210-B1 | SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2021-06-23 | — | — | EP | claimed |
| US-20210053031-A1 | HETEROGENEOUS CATALYSTS FOR THE SYNTHESIS OF CARBAMATES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-02-25 | — | — | US | claimed |
| CN-105229015-B | Zinc cluster compounds and their use as catalysts in the reaction of amines with dialkyl carbonates | 科思创德国股份公司 | 2020-11-03 | — | — | CN | claimed |
| US-10807084-B2 | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | COVESTRO DEUTSCHLAND AG (DE) | 2020-10-20 | — | — | US | claimed |
| US-20200147594-A1 | SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | COVESTRO DEUTSCHLAND AG (DE) | 2020-05-14 | — | — | US | claimed |
| EP-3625210-A1 | SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | Covestro Deutschland AG (DE) | 2020-03-25 | — | — | EP | claimed |
| CN-110650944-A | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | 科思创德国股份有限公司 | 2020-01-03 | — | — | CN | claimed |
| US-20160194277-A1 | ZINC CLUSTER COMPOUNDS AND THEIR USE AS CATALYSTS IN THE REACTION OF AMINES WITH DIALKYL CARBONATES | COVESTRO DEUTSCHLAND AG (DE) | 2016-07-07 | — | — | US | claimed |
| EP-2999705-A1 | ZINC CLUSTER COMPOUNDS AND THEIR USE AS CATALYSTS IN THE REACTION OF AMINES WITH DIALKYL CARBONATES | Covestro Deutschland AG (DE) | 2016-03-30 | — | — | EP | claimed |
| US-9278906-B2 | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | BAYER MATERIALSCIENCE AG (DE) | 2016-03-08 | — | — | US | claimed |
| CN-105229015-A | Zinc cluster compounds and their use as catalysts in the reaction of amines with dialkyl carbonates | BAYER MATERIALSCIENCE AG | 2016-01-06 | — | — | CN | claimed |
| EP-2905273-A1 | Process for hydrogenating aromatic di- and polyamines | Bayer MaterialScience AG (DE) | 2015-08-12 | — | — | EP | claimed |
| EP-2905272-A1 | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | Bayer MaterialScience AG (DE) | 2015-08-12 | — | — | EP | claimed |
| US-20150218082-A1 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2015-08-06 | — | — | US | claimed |
| US-20150218083-A1 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES TO CYCLOALIPHATIC DI- AND POLYAMINES | COVESTRO DEUTSCHLAND AG (DE) | 2015-08-06 | — | — | US | claimed |
| CN-104817460-A | Process for hydrogenating aromatic di- and polyamines | BAYER MATERIALSCIENCE AG | 2015-08-05 | — | — | CN | claimed |
| CN-104817459-A | Process for hydrogenating aromatic di- and polyamines to cycloaliphatic di- and polyamines | BAYER MATERIALSCIENCE AG | 2015-08-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147594-A1 | SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | CDYL, ZYX, CXXC4 | TDP1 4407/4885APP 2694/4885MAPT 3375/4885 |
| US-20150218083-A1 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES TO CYCLOALIPHATIC DI- AND POLYAMINES | DDT, HRH3, HRH4 | TDP1 2325/4885APP 2745/4885MAPT 2582/4885 |
| US-20210053031-A1 | HETEROGENEOUS CATALYSTS FOR THE SYNTHESIS OF CARBAMATES | SCO2, CDYL, PYM1 | TDP1 2099/4885APP 4125/4885MAPT 1340/4885 |
| US-11406964-B2 | Heterogeneous catalysts for the synthesis of carbamates | SCO2, CDYL, PYM1 | TDP1 2099/4885APP 4125/4885MAPT 1340/4885 |
| US-20150218082-A1 | PROCESS FOR HYDROGENATING AROMATIC DI- AND POLYAMINES | HNMT, DDT, HRH3 | TDP1 2534/4885APP 3332/4885MAPT 3358/4885 |
| US-20160194277-A1 | ZINC CLUSTER COMPOUNDS AND THEIR USE AS CATALYSTS IN THE REACTION OF AMINES WITH DIALKYL CARBONATES | AOC1, AOC2, ODC1 | TDP1 4060/4885APP 3323/4885MAPT 4142/4885 |
| US-10807084-B2 | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | CDYL, ZYX, CXXC4 | TDP1 4407/4885APP 2694/4885MAPT 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.