Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19749284 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL19244141 | 0.86 | MAPT (0.51) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL19265821 | 0.84 | PKM (0.44) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL8154893 | 0.84 | LMNA (0.47) | PKMSMN1; SMN2LMNAESR1ADORA3 | |
| SCHEMBL19244145 | 0.82 | LMNA (0.46) | SMN1; SMN2MAPK1TSHRLMNAESR1 | |
| SCHEMBL19265822 | 0.82 | CA1 (0.42) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL2825992 | 0.81 | LMNA (0.45) | SMN1; SMN2MAPK1TSHRLMNAESR1 | |
| SCHEMBL19749283 | 0.79 | BCHE (0.38) | SMN1; SMN2MAPK1TSHRLMNAESR1 | |
| SCHEMBL19697409 | 0.78 | AKT1 (0.53) | SMN1; SMN2LMNAESR1ADORA3CDC25A | |
| SCHEMBL19749285 | 0.78 | CA2 (0.53) | SMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208275-B1 | PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND AND PHOSPHORYLCHOLINE COMPLEX | NOF CORP (JP) | 2019-01-09 | — | — | EP | disclosed |
| US-9850266-B2 | Phosphorylcholine group-containing compound and phosphorylcholine complex | NOF CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-9850266-B2 | Phosphorylcholine group-containing compound and phosphorylcholine complex | NOF CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20170240576-A1 | Phosphorylcholine Group-Containing Compound and Phosphorylcholine Complex | NOF CORPORATION (JP) | 2017-08-24 | — | — | US | disclosed |
| EP-3208275-A1 | PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND AND PHOSPHORYLCHOLINE COMPLEX | NOF Corporation (JP) | 2017-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240576-A1 | Phosphorylcholine Group-Containing Compound and Phosphorylcholine Complex | PHOSPHO1, PCTP, PLA2G2C | PKM 1011/4885SMN1; SMN2 2774/4885MAPK1 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.