Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644777 | 0.77 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL23457247 | 0.76 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL7756808 | 0.76 | TDP1 (0.44) | TDP1ALDH1A1PKM | |
| SCHEMBL30994052 | 0.73 | TDP1 (0.41) | TDP1ALDH1A1PKM | |
| SCHEMBL28834352 | 0.67 | — | — | |
| SCHEMBL19364260 | 0.67 | NOTUM (0.38) | TDP1ALDH1A1 | |
| SCHEMBL29549708 | 0.66 | — | — | |
| SCHEMBL194096 | 0.66 | — | — | |
| SCHEMBL21397288 | 0.64 | TDP1 (0.38) | TDP1 | |
| SCHEMBL25881090 | 0.64 | TDP1 (0.38) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119531137-A | Moisture-conducting cool fabric for sportswear and preparation method thereof | 广东翔麒福实业有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-113088054-B | Polylactic acid material containing continuous conductive structure and preparation method thereof | 湖南绿斯达生物科技有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-113088054-A | Polylactic acid material containing continuous conductive structure and preparation method thereof | 湖南绿斯达生物科技有限公司 | 2021-07-09 | — | — | CN | claimed |
| EP-4719386-A2 | 5,6 SATURATED BICYCLIC HETEROCYLES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | Merck Sharp & Dohme LLC (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260028347-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2026-01-29 | — | — | US | disclosed |
| EP-4656635-A1 | SUBSTITUTED BENZENE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2025-12-03 | — | — | EP | disclosed |
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| CN-119531137-A | Moisture-conducting cool fabric for sportswear and preparation method thereof | 广东翔麒福实业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119531137-A | Moisture-conducting cool fabric for sportswear and preparation method thereof | 广东翔麒福实业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2024249539-A1 | 5,6 UNSATURATED BICYCLIC HETEROCYLES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024249389-A2 | 5,6 SATURATED BICYCLIC HETEROCYLES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2024-12-05 | — | — | WO | disclosed |
| US-11858941-B2 | Heterocyclic and heteroaryl compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2023009816-A1 | HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| CN-113088054-B | Polylactic acid material containing continuous conductive structure and preparation method thereof | 湖南绿斯达生物科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-20210238186-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS HD, INC. | 2021-08-05 | — | — | US | disclosed |
| US-20210238186-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS HD, INC. | 2021-08-05 | — | — | US | disclosed |
| CN-113088054-A | Polylactic acid material containing continuous conductive structure and preparation method thereof | 湖南绿斯达生物科技有限公司 | 2021-07-09 | — | — | CN | disclosed |
| EP-3814357-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| CN-112654625-A | Heterocyclic and heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2021-04-13 | — | — | CN | disclosed |
| WO-2017133665-A1 | 6,7-DIAZAINDAZOLE AND 6,7-DIAZAINDOLE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028347-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TDP1 240/4885ALDH1A1 1288/4885PKM 2191/4885 |
| US-11858941-B2 | Heterocyclic and heteroaryl compounds for treating Huntington's disease | HTT, HYPK, FH | TDP1 384/4885ALDH1A1 1719/4885PKM 1508/4885 |
| US-20210238186-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, FH | TDP1 384/4885ALDH1A1 1719/4885PKM 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.