Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211183 | 0.83 | ASIC3 (0.42) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| Hydrochloric Acid SCHEMBL19211215 | 0.82 | ASIC3 (0.41) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| SCHEMBL19248871 | 0.77 | DRD4 (0.50) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| SCHEMBL19249246 | 0.72 | GHSR (0.61) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| SCHEMBL19211279 | 0.71 | GHSR (0.46) | DRD4GRM5ALDH1A1CTSVCTSL | |
| SCHEMBL19211285 | 0.71 | GRM5 (0.45) | DRD4GRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL19211219 | 0.70 | GABRA1 (0.47) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| SCHEMBL19211211 | 0.69 | DRD4 (0.42) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| SCHEMBL19211213 | 0.69 | GRM5 (0.47) | DRD4GRIN2DGRIN3BADRB2CHRM2 | |
| SCHEMBL19249206 | 0.68 | DRD4 (0.39) | DRD4GRIN2DGRIN3BADRB2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139274-A1 | QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-08-17 | — | — | WO | disclosed |