Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.42 |
| ▸ | TDO2 | P48775 | 9/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249079 | 0.76 | IDO1 (0.45) | IDO1TDO2MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL27376604 | 0.75 | CA12 (0.43) | IDO1TDO2 | |
| SCHEMBL19249080 | 0.74 | IDO1 (0.51) | IDO1TDO2 | |
| SCHEMBL21552096 | 0.72 | DHPS (0.62) | RXFP1DHPSSMN1; SMN2 | |
| SCHEMBL30797862 | 0.72 | IDO1 (0.42) | IDO1TDO2 | |
| SCHEMBL16845740 | 0.71 | PTGER1 (0.46) | MAPK1CYP2C9PTGER1MAPT | |
| SCHEMBL470163 | 0.70 | TDO2 (0.50) | IDO1TDO2FBP1 | |
| SCHEMBL19249081 | 0.70 | MAPT (0.46) | IDO1TDO2CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL19248986 | 0.69 | CCR5 (0.48) | IDO1TDO2MAPTSMN1; SMN2 | |
| SCHEMBL19249340 | 0.69 | PTGER1 (0.37) | IDO1TDO2FBP1MAPK1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |