Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 4/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477152 | 0.82 | ESR1 (0.48) | ELANEALDH1A1GAASMN1; SMN2ESR1 | |
| SCHEMBL13706058 | 0.81 | ELANE (0.34) | ELANEALDH1A1GAASMN1; SMN2ESR1 | |
| SCHEMBL13161550 | 0.76 | ESR1 (0.41) | ELANEGAASMN1; SMN2ESR1ESR2 | |
| SCHEMBL15179698 | 0.73 | LMNA (0.37) | ELANEALDH1A1 | |
| SCHEMBL12205969 | 0.73 | ELANE (0.41) | ELANEALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL21973906 | 0.70 | ELANE (0.50) | ELANESMN1; SMN2ESR1 | |
| SCHEMBL14219266 | 0.70 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2HSD17B10PGR | |
| SCHEMBL13486819 | 0.68 | LPAR1 (0.42) | ALDH1A1KCNK3KCNK9HSD17B10MAPK1 | |
| SCHEMBL25524624 | 0.68 | CA1 (0.35) | ELANEALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14477148 | 0.68 | KDM4E (0.34) | ELANEALDH1A1GAAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081988-B1 | NEGATIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2017-08-16 | — | — | EP | disclosed |