Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251428 | 0.92 | MAPT (0.33) | MAPT | |
| SCHEMBL19251433 | 0.86 | PIK3R1 (0.36) | MAPT | |
| SCHEMBL23287685 | 0.61 | FAAH (0.36) | FAAHMGLL | |
| SCHEMBL19252635 | 0.60 | PIK3R1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL12943784 | 0.59 | PIK3CD (0.43) | MAPTFAAHMGLLMAT2AALDH1A1 | |
| SCHEMBL24168172 | 0.58 | KDM4E (0.32) | MAPTALDH1A1 | |
| SCHEMBL16597050 | 0.56 | NOTUM (0.47) | MAPTSLC6A2FAAHMGLLTP53 | |
| SCHEMBL5412834 | 0.56 | GABRA1 (0.44) | — | |
| SCHEMBL91279 | 0.55 | PNMT (0.62) | ALDH1A1 | |
| SCHEMBL4058855 | 0.54 | SLC6A2 (0.41) | MAPTSLC6A2FAAHMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |