Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 8/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251427 | 0.86 | MAPT (0.36) | MAPT | |
| SCHEMBL19251428 | 0.85 | MAPT (0.33) | MAPT | |
| SCHEMBL29109339 | 0.77 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109342 | 0.77 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252635 | 0.72 | PIK3R1 (0.48) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109273 | 0.69 | PIK3R1 (0.33) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109275 | 0.69 | PIK3R1 (0.33) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL24168172 | 0.68 | KDM4E (0.32) | MAPT | |
| SCHEMBL19251435 | 0.66 | GRIA2 (0.32) | — | |
| SCHEMBL19251425 | 0.65 | LMNA (0.36) | PIK3R1PIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |