Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830224 | 0.89 | TDP1 (0.43) | TDP1ALDH1A1KDM4ETRPM8RAB9A | |
| SCHEMBL6830347 | 0.87 | HTT (0.52) | TDP1ALDH1A1KDM4ETRPM8RAB9A | |
| SCHEMBL19868597 | 0.85 | MEN1 (0.46) | ALDH1A1KDM4ETRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL1259294 | 0.82 | PDK1 (0.50) | TDP1ALDH1A1TRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL1927316 | 0.81 | TDP1 (0.57) | TDP1ALDH1A1KDM4ETRPM8RAB9A | |
| SCHEMBL17078095 | 0.81 | TSHR (0.48) | TDP1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL19415907 | 0.81 | RAB9A (0.43) | TDP1ALDH1A1KDM4ETRPM8RAB9A | |
| SCHEMBL19868565 | 0.81 | NR3C1 (0.53) | ALDH1A1KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL22292871 | 0.81 | ALDH1A1 (0.44) | TDP1ALDH1A1KDM4ETRPM8RAB9A | |
| SCHEMBL19868441 | 0.80 | RAB9A (0.44) | TDP1ALDH1A1KDM4ETRPM8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300407-B2 | CARBAMATES DERIVED FROM ARYLALKYLAMINES | S A L V A T LAB SA (ES) | 2011-06-08 | — | — | EP | claimed |
| EP-1300407-B2 | CARBAMATES DERIVED FROM ARYLALKYLAMINES | S A L V A T LAB SA (ES) | 2011-06-08 | — | — | EP | disclosed |