SCHEMBL1925165

SCHEMBL1925165

C=C(C)CCn1cnc2ncnc-2c1N

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AHCY P23526 3/20 0.31
ADORA2A P29274 5/20 0.31
ADORA1 P30542 2/20 0.31
ADORA2B P29275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149409 0.81 ADORA2B (0.34) ADORA2AADORA1ADORA2B
SCHEMBL1276952 0.76 ADORA2A (0.46) AHCYADORA2AADORA1ADORA2B
SCHEMBL1914 0.70 ADORA2A (0.41) ADORA2AADORA1
SCHEMBL18642496 0.69 ADORA2A (0.54) AHCYADORA2AADORA1ADORA2B
SCHEMBL3731609 0.67 ADORA2A (0.52) ADORA2A
SCHEMBL9405169 0.66 AHCY (0.32) AHCY
SCHEMBL5960487 0.60 MEN1 (0.30)
SCHEMBL1997511 0.57 ADORA2A (0.32) ADORA2AADORA1
SCHEMBL7304399 0.56 KDM4E (0.40) ADORA2AADORA1
SCHEMBL8840648 0.56 ADORA2A (0.33) ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464628-A1 TARGET REPORTER CONSTRUCTS AND USES THEREOF RedVault Biosciences LP (US) 2019-04-10 EP disclosed
WO-2017214127-A1 TARGET REPORTER CONSTRUCTS AND USES THEREOF REDVAULT BIOSCIENCES, LP (US) 2017-12-14 WO disclosed
EP-2326707-A2 METHOD FOR PRODUCTION OF ISOPRENOIDS Allylix, Inc. (US) 2011-06-01 EP disclosed
WO-2010019696-A2 METHOD FOR PRODUCTION OF ISOPRENOIDS ALLYLIX, INC. (US) 2010-02-18 WO disclosed