Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053573 | 0.86 | THRB (0.42) | THRB | |
| SCHEMBL19252726 | 0.84 | ESR1 (0.31) | — | |
| SCHEMBL7898585 | 0.69 | PGK1 (0.37) | THRB | |
| SCHEMBL4012544 | 0.67 | — | — | |
| Perflexane SCHEMBL20530384 | 0.67 | THRB (0.48) | THRB | |
| Phosphonic Acid SCHEMBL20530381 | 0.67 | THRB (0.48) | THRB | |
| Perflexane SCHEMBL20530385 | 0.67 | THRB (0.48) | THRB | |
| Phosphonic Acid SCHEMBL20530382 | 0.67 | THRB (0.48) | THRB | |
| Perflexane SCHEMBL1409103 | 0.65 | THRB (0.46) | THRB | |
| Perflexane SCHEMBL1409099 | 0.65 | THRB (0.46) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48165-E1 | Alkenyl (perfluoroalkyl) phosphinic acids | MERCK PATENT GMBH (DE) | 2020-08-18 | — | — | US | disclosed |
| US-10160777-B2 | Alkenyl(perfluoroalkyl)phosphinic acids | MERCK PATENT GMBH (DE) | 2018-12-25 | — | — | US | disclosed |
| US-20170240574-A1 | ALKENYL (PERFLUOROALKYL) PHOSPHINIC ACIDS | MERCK PATENT GMBH (DE) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160777-B2 | Alkenyl(perfluoroalkyl)phosphinic acids | PHOSPHO1, PFAS, SLCO4C1 | THRB 3203/4885 |
| US-20170240574-A1 | ALKENYL (PERFLUOROALKYL) PHOSPHINIC ACIDS | PHOSPHO1, PFAS, SLCO4C1 | THRB 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.