Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498781 | 0.89 | PPARG (0.51) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL19743142 | 0.87 | CA1 (0.48) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL29386613 | 0.85 | PPARG (0.47) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL498671 | 0.85 | PPARG (0.47) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL498873 | 0.79 | PPARG (0.46) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL29379677 | 0.79 | PPARG (0.46) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL20932824 | 0.78 | PPARG (0.80) | PPARGPPARDPPARAMEN1ALDH1A1 | |
| SCHEMBL3969744 | 0.76 | CTSL (0.55) | MEN1ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL3962833 | 0.76 | PPARG (0.38) | PPARGPPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL498905 | 0.75 | PPARG (0.44) | PPARGPPARDPPARAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10792277-B2 | Methods of treatment of fibrosis and cancers | GENFIT (FR) | 2020-10-06 | — | — | US | disclosed |
| US-20170239213-A1 | METHODS OF TREATMENT OF FIBROSIS AND CANCERS | GENFIT (FR) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170239213-A1 | METHODS OF TREATMENT OF FIBROSIS AND CANCERS | MMP1, COL1A1, MMP8 | PPARG 344/4885PPARD 1060/4885PPARA 446/4885 |
| US-10792277-B2 | Methods of treatment of fibrosis and cancers | MMP1, COL1A1, MMP8 | PPARG 344/4885PPARD 1060/4885PPARA 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.