SCHEMBL19253312

SCHEMBL19253312

Oc1c(O)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
PDE4B Q07343 4/20 0.48
PDE4A P27815 3/20 0.48
PDE4C Q08493 3/20 0.48
PDE4D Q08499 3/20 0.48
BCL2L1 Q07817 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HNF4A P41235 1/20 0.46
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
MMP3 P08254 1/20 0.46
BACE1 P56817 1/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8644874 0.97 PDE4A (0.50) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL4598394 0.91 PDE4B (0.56) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL14353864 0.91 PDE4B (0.50) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL454643 0.88 PDE4B (0.54) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL11786814 0.88 HDAC4 (0.54) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL1754108 0.88 PDE4B (0.52) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL27577881 0.83 SENP1 (0.46) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL29001722 0.81 PDE4B (0.58) HDAC4HDAC2HDAC8HDAC6PDE4B
SCHEMBL29287283 0.81 MMP3 (0.67) PDE4BPDE4APDE4CPDE4DBCL2L1
SCHEMBL6521508 0.81 HDAC4 (0.47) HDAC4HDAC2HDAC8HDAC6PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026889-A1 TWO DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS U.S. GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2025-01-23 US disclosed
US-12110367-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2024-10-08 US disclosed
US-20200148827-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2020-05-14 US disclosed
US-10590241-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2020-03-17 US disclosed
US-20170240706-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2017-08-24 US disclosed