Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584037 | 0.92 | CD44 (0.56) | CD44KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL31255799 | 0.84 | CD44 (0.56) | CD44KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL10915062 | 0.84 | POLB (0.47) | CD44KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL30079667 | 0.83 | KDM4E (0.52) | KDM4EKMT2AMEN1TDP1CYP3A4 | |
| SCHEMBL4628056 | 0.83 | SORT1 (0.46) | KDM4EKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL3031603 | 0.83 | CYP3A4 (0.52) | KDM4EKMT2AMEN1TDP1CYP3A4 | |
| SCHEMBL974647 | 0.83 | KDM4E (0.52) | KDM4EKMT2AMEN1TDP1CYP3A4 | |
| SCHEMBL18669166 | 0.81 | SLC9A1 (0.58) | KDM4EKMT2AMEN1TDP1CYP3A4 | |
| SCHEMBL31277421 | 0.81 | ALDH1A1 (0.51) | KDM4EKMT2AMEN1TDP1CYP3A4 | |
| SCHEMBL29087117 | 0.81 | SORT1 (0.45) | KDM4EKMT2AMEN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026769-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2025-01-23 | — | — | US | disclosed |
| EP-4423081-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | The Children's Medical Center Corporation (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118201920-A | PAPD5 inhibitors and methods of use thereof | 儿童医疗中心公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023086220-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-2842946-B1 | QUINAZOLINEDIONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |
| CN-100537222-C | Solvent stable tinted iridescent film | ENGELHARD CORP (US) | 2009-09-09 | — | — | CN | disclosed |
| US-20070269641-A1 | Solvent Stable Tinted Iridescent Film | GRANEY DANIEL J | 2007-11-22 | — | — | US | disclosed |
| CN-1839038-A | Solvent stable tinted iridescent film | ENGELHARD CORP (US) | 2006-09-27 | — | — | CN | disclosed |
| EP-1656252-A1 | SOLVENT STABLE TINTED IRIDESCENT FILM | Engelhard Corporation (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005018931-A1 | SOLVENT STABLE TINTED IRIDESCENT FILM | ENGELHARD CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |
| EP-0914386-B1 | PIGMENT COMPOSITIONS | ENGELHARD CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| US-5669967-A | MONOAZO DYES, PYRAZOLE DYES FOR INKS, PAINTS AND PLASTICS | ENGELHARD CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250026769-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | POT1, PARP15, TERT | CD44 2947/4885KDM4E 2544/4885KMT2A 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.