SCHEMBL19253605

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19253695	0.90	NPC1 (0.59)	LRRK2KMT2AMEN1NPC1RAB9A
	SCHEMBL19253687	0.89	TAS1R3 (0.57)	LRRK2KMT2AMEN1MMP13NPC1
	SCHEMBL19253774	0.88	LRRK2 (0.61)	LRRK2KMT2AMEN1NPC1RAB9A
	SCHEMBL19253737	0.84	LRRK2 (0.44)	LRRK2KMT2AMEN1NPC1RAB9A
	SCHEMBL19253738	0.83	MEN1 (0.45)	LRRK2KMT2AMEN1NPC1RAB9A
	SCHEMBL19270396	0.82	LRRK2 (0.63)	LRRK2KMT2AMEN1MMP13NPC1
	SCHEMBL19253769	0.82	SCD (0.63)	LRRK2KMT2AMEN1NPC1RAB9A
	SCHEMBL19253623	0.82	RAF1 (0.43)	LRRK2NPC1RAB9AMAPTCASP3
	SCHEMBL19253659	0.82	RAB9A (0.65)	KMT2AMEN1NPC1RAB9ANPSR1
	SCHEMBL19253669	0.81	NPC1 (0.44)	LRRK2KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.