Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336769 | 0.88 | TRPM8 (0.45) | TRPM8KMT2ATSPOTSHRMAPK1 | |
| SCHEMBL11868335 | 0.81 | TSPO (0.51) | TRPM8KMT2ATSPOTSHRMAPK1 | |
| SCHEMBL3062067 | 0.81 | TRPM8 (0.50) | TRPM8KMT2ATSHRMAPK1RAB9A | |
| SCHEMBL7236532 | 0.79 | TSPO (0.47) | TRPM8KMT2ATSPOTSHRNPC1 | |
| SCHEMBL1927316 | 0.78 | TDP1 (0.57) | TRPM8TSPOTSHRNPC1RAB9A | |
| SCHEMBL16435054 | 0.77 | KMT2A (0.44) | TRPM8KMT2ATSPONPC1RAB9A | |
| SCHEMBL28995154 | 0.75 | TRPM8 (0.47) | TRPM8KMT2ATSPOTSHRMAPK1 | |
| SCHEMBL11562806 | 0.75 | TSHR (0.44) | TRPM8KMT2ATSPOTSHRMAPK1 | |
| SCHEMBL14678140 | 0.75 | ALDH1A1 (0.76) | TRPM8KMT2ATSPOTSHRMAPK1 | |
| SCHEMBL25413920 | 0.74 | ALDH1A1 (0.44) | TRPM8KMT2ATSPONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300407-B2 | CARBAMATES DERIVED FROM ARYLALKYLAMINES | S A L V A T LAB SA (ES) | 2011-06-08 | — | — | EP | claimed |