Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925384 | 0.79 | TRPM8 (0.57) | TSPOTRPM8LMNANPC1RAB9A | |
| SCHEMBL1927316 | 0.71 | TDP1 (0.57) | TSPOTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL1927016 | 0.71 | ALDH1A1 (0.69) | TSPOTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL1926093 | 0.69 | TSHR (0.51) | TSPOTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL1259310 | 0.69 | PDK1 (0.58) | TRPM8NPC1RAB9AALDH1A1HTT | |
| SCHEMBL29009652 | 0.69 | TSHR (0.49) | TSPOTRPM8NPC1RAB9AKMT2A | |
| SCHEMBL2457272 | 0.69 | PDK1 (0.54) | TSPOTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL6647621 | 0.68 | LMNA (0.57) | LMNANPC1RAB9AALDH1A1HTT | |
| SCHEMBL16435054 | 0.68 | KMT2A (0.44) | TSPOTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL4237595 | 0.68 | CNR2 (0.58) | TSPONPC1RAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | TSPO 1662/4885TRPM8 1328/4885LMNA 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.