Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27020103 | 0.69 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL19086066 | 0.67 | KMT2A (0.39) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL20680892 | 0.66 | PKM (0.45) | LMNAMAPTALDH1A1PKMMEN1 | |
| SCHEMBL18038909 | 0.66 | ALDH1A1 (0.49) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL30003208 | 0.64 | L3MBTL1 (0.48) | LMNAMAPTALDH1A1GAAMEN1 | |
| SCHEMBL19337137 | 0.64 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1PKMMEN1 | |
| SCHEMBL23524981 | 0.63 | AAK1 (0.47) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL23524984 | 0.63 | AAK1 (0.47) | LMNAMAPTALDH1A1GAAPKM | |
| SCHEMBL19239593 | 0.63 | ALDH1A1 (0.42) | MAPTALDH1A1GAAPKMMEN1 | |
| SCHEMBL28482889 | 0.62 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205650-A1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2017-08-16 | — | — | EP | disclosed |