Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365281 | 0.77 | TRPA1 (0.38) | TRPA1TRPM8 | |
| SCHEMBL598497 | 0.76 | — | — | |
| SCHEMBL598630 | 0.71 | CA1 (0.46) | TRPA1TRPM8 | |
| SCHEMBL24031427 | 0.69 | CA1 (0.43) | TRPA1TRPM8 | |
| SCHEMBL25612783 | 0.69 | TRPA1 (0.35) | TRPA1TRPM8 | |
| SCHEMBL24142309 | 0.69 | CA1 (0.33) | — | |
| SCHEMBL5776136 | 0.67 | TRPA1 (0.41) | TRPA1TRPM8 | |
| SCHEMBL16743130 | 0.66 | TRPA1 (0.46) | TRPA1TRPM8 | |
| SCHEMBL853466 | 0.66 | TRPA1 (0.46) | TRPA1TRPM8 | |
| Formamide SCHEMBL28320537 | 0.65 | TRPA1 (0.38) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920054-B2 | Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | PFIZER INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170233390-A1 | Methyl- and Trifluoromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof | PFIZER INC. (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233390-A1 | Methyl- and Trifluoromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof | RORC, RORB, RORA | TRPA1 1215/4885TRPM8 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.