Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | PGK2 | P07205 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13375622 | 0.92 | MAPK1 (0.50) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL9508370 | 0.83 | MAPK1 (0.76) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL2865735 | 0.81 | MAPK1 (0.81) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL44643 | 0.81 | MAPK1 (0.58) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL8414583 | 0.81 | MAPK1 (0.58) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL44954 | 0.80 | MAPK1 (0.44) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL31578994 | 0.79 | MAPK1 (0.56) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL6348661 | 0.79 | MAPK1 (0.50) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| Hydrogen Peroxide SCHEMBL20240069 | 0.77 | MAPK1 (0.60) | MAPK1ESR1ESR2ALDH1A1ALOX15 | |
| SCHEMBL19327212 | 0.77 | MAPK1 (0.60) | MAPK1ESR1ESR2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205698-A1 | FUNCTIONALIZED OLEFIN INTERPOLYMERS, COMPOSITIONS AND ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME | Dow Global Technologies LLC (US) | 2017-08-16 | — | — | EP | disclosed |