Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | PGK1 | P00558 | 2/20 | 0.38 |
| ▸ | PGK2 | P07205 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23152257 | 0.84 | MAPK1 (0.73) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL11666048 | 0.83 | KIF11 (0.41) | MAPK1ALDH1A1ALOX15HDAC4HDAC2 | |
| SCHEMBL2969176 | 0.81 | ALDH1A1 (0.70) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| Tert-Butyl Hydroperoxide SCHEMBL11212401 | 0.81 | MAPK1 (0.50) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL29764513 | 0.80 | MAPK1 (0.52) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| Hydrogen Peroxide SCHEMBL20240069 | 0.80 | MAPK1 (0.60) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL2865735 | 0.79 | MAPK1 (0.81) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL44643 | 0.79 | MAPK1 (0.58) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL8414583 | 0.79 | MAPK1 (0.58) | MAPK1ALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL19255653 | 0.79 | MAPK1 (0.52) | MAPK1ALDH1A1ALOX15ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960698-B2 | Method for treating tar | SUMITOMO CHEMICAL COMPNAY, LIMTED (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20030183557-A1 | Method for treating tar | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-10-02 | — | — | US | disclosed |