Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255178 | 0.86 | MAPK1 (0.31) | — | |
| SCHEMBL19255555 | 0.82 | — | — | |
| SCHEMBL19255752 | 0.81 | CHEK1 (0.36) | EGFRSGK1 | |
| SCHEMBL9977698 | 0.81 | PIK3CG (0.35) | — | |
| SCHEMBL19255585 | 0.76 | REN (0.34) | — | |
| SCHEMBL17518517 | 0.75 | AR (0.46) | — | |
| SCHEMBL786095 | 0.75 | GPR84 (0.40) | EGFRMAPK14SGK1 | |
| SCHEMBL19250804 | 0.73 | NOS3 (0.33) | — | |
| SCHEMBL19250682 | 0.73 | SGK1 (0.33) | SGK1 | |
| SCHEMBL19886542 | 0.73 | TNKS (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |