Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 2/20 | 0.49 |
| ▸ | TYK2 | P29597 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255780 | 0.84 | F2R (0.60) | GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30739749 | 0.80 | JAK2 (0.71) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19576334 | 0.80 | GAA (0.56) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL16584740 | 0.79 | F10 (0.43) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19209037 | 0.78 | GAA (0.44) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19209038 | 0.78 | GAA (0.44) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19935743 | 0.76 | KMT2A (0.49) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL19576325 | 0.76 | KMT2A (0.49) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL16346420 | 0.76 | GAA (0.59) | GAAJAK2JAK1TYK2HTT | |
| SCHEMBL16345869 | 0.76 | GAA (0.48) | GAAJAK2JAK1TYK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191608-A1 | NOVEL PROCESS FOR PREPARATION OF IDELALISIB | LAURUS LABS LIMITED (IN) | 2017-11-09 | — | — | WO | disclosed |