SCHEMBL192561

SCHEMBL192561

COc1nc(O)nc(O)n1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 2/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
TSHR P16473 1/20 0.34
RECQL P46063 1/20 0.34
CYP1A2 P05177 2/20 0.32
FTO Q9C0B1 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 2/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329816 0.94 LMNA (0.35) LMNATDP1MEN1KMT2AATM
SCHEMBL13173439 0.84 GAA (0.40) LMNATDP1MEN1KMT2AATM
SCHEMBL2633403 0.82 CYP1A2 (0.44) LMNATDP1TSHRCYP1A2FTO
SCHEMBL11321577 0.80 LMNA (0.33) LMNATDP1MEN1KMT2AATM
SCHEMBL14136140 0.78
SCHEMBL33145 0.75 ALDH1A1 (0.43) LMNATDP1MEN1KMT2AATM
SCHEMBL1426652 0.73
SCHEMBL11212319 0.71
SCHEMBL1285445 0.71 LMNA (0.42) LMNATDP1MEN1KMT2AATM
SCHEMBL276187 0.71 TDP1 (0.35) LMNATDP1MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324663-A Efficient synthesis process for preparing methyl cyanamide from cyanamide 安徽东至广信农化有限公司 2024-07-12 CN claimed
CN-118307445-A Green preparation method of cyanamide-based methyl carbamate 安徽东至广信农化有限公司 2024-07-09 CN claimed
CN-116730872-A Process for synthesizing methyl cyanamide 安徽东至广信农化有限公司 2023-09-12 CN claimed
CN-116396227-A 2-amino substituted bendamustine derivative with HDAC (high-voltage analog to digital converter) inhibition effect, and preparation method and application thereof 江苏省人民医院(南京医科大学第一附属医院) 2023-07-07 CN claimed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US claimed
US-4208320-A Flame retardant resin composition comprising reaction product of polyguanamine compound and cyanuric or isocyanuric acid compound ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-06-17 US claimed
US-3980616-A Flameproofing agent for polyamide resins MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-09-14 US claimed
CN-118359518-A Preparation method of high-purity methyl cyanocarbamate 安徽东至广信农化有限公司 2024-07-19 CN disclosed
CN-118324663-A Efficient synthesis process for preparing methyl cyanamide from cyanamide 安徽东至广信农化有限公司 2024-07-12 CN disclosed
CN-118307445-A Green preparation method of cyanamide-based methyl carbamate 安徽东至广信农化有限公司 2024-07-09 CN disclosed
CN-118307445-A Green preparation method of cyanamide-based methyl carbamate 安徽东至广信农化有限公司 2024-07-09 CN disclosed
US-11945928-B2 Polyol composition and polyurethane foam SEKISUI CHEMICAL CO., LTD. (JP) 2024-04-02 US disclosed
CN-115504985-B Synthesis method of epinastine hydrochloride 重庆美莱德生物医药有限公司 2024-01-19 CN disclosed
US-4393060-A ANTICANCER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1983-07-12 US disclosed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US disclosed
US-4256558-A EXTRUSION OF A BLEND OF POLYETHYLENE TEREPHTHALATE AND A DIALLYL COMPOUND FOLLOWED BY RADIATION CURING; FILMS AND FILAMENTS HAVING GOOD HEAT RESISTANCE AND PHOTOSTABILITY TEIJIN LIMITED (JP) 1981-03-17 US disclosed
US-4249004-A FIREPROOFING FOR POLYMERS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-02-03 US disclosed
EP-0015441-A2 Laminated film structure of aromatic polyester and process for production thereof TEIJIN LIMITED (JP) 1980-09-17 EP disclosed
US-4208320-A Flame retardant resin composition comprising reaction product of polyguanamine compound and cyanuric or isocyanuric acid compound ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-06-17 US disclosed
US-3980616-A Flameproofing agent for polyamide resins MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-09-14 US disclosed