SCHEMBL1925655

SCHEMBL1925655

CC1(c2cc3ccccc3[nH]2)NC(=O)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 1/20 0.47
BRD4 O60885 1/20 0.44
LMNA P02545 1/20 0.41
TNKS O95271 1/20 0.41
DAO P14920 2/20 0.40
DDO Q99489 1/20 0.40
KDR P35968 2/20 0.38
CHEK1 O14757 1/20 0.38
B3GNT2 Q9NY97 1/20 0.38
FLT3 P36888 1/20 0.38
CYP2A6 P11509 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
PDGFRB P09619 1/20 0.37
FGFR1 P11362 1/20 0.37
AOC3 Q16853 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA3 P07451 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542484 0.71 LMNA (0.70) PTGER3LMNATNKSMAPTALDH1A1
SCHEMBL7601873 0.70 HRH4 (0.37) BRD4LMNADAODDOKDR
SCHEMBL6096901 0.69 AOC3 (0.44) BRD4DAODDOFLT3CYP2A6
SCHEMBL4384462 0.69 ALDH1A1 (0.59) LMNATNKSMAPTALDH1A1
SCHEMBL542865 0.69 ALDH1A1 (0.59) LMNATNKSMAPTALDH1A1
SCHEMBL4384456 0.69 ALDH1A1 (0.59) LMNATNKSMAPTALDH1A1
SCHEMBL542713 0.68 PTGER3 (0.49) PTGER3LMNATNKSKDM4EMAPT
SCHEMBL7631274 0.68 LMNA (0.57) PTGER3LMNATNKSCYP2A6KDM4E
SCHEMBL13948374 0.68 PTGER3 (0.46) PTGER3LMNATNKS
SCHEMBL79379 0.68 LMNA (0.57) PTGER3LMNATNKSCYP2A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772513-B D-carbamyl hydrolase mutant, gene, expression vector and application thereof 江南大学 2025-05-02 CN disclosed
CN-115772513-B D-carbamyl hydrolase mutant, gene, expression vector and application thereof 江南大学 2025-05-02 CN disclosed
CN-114686464-B Application of D-N-carbamyl hydrolase in production of D-tryptophan 湖南引航生物科技有限公司 2023-11-28 CN disclosed
EP-1188826-B1 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids AJINOMOTO KK (JP) 2011-06-08 EP disclosed
US-7582454-B2 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO. INC. (JP) 2009-09-01 US disclosed
US-20060246553-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2006-11-02 US disclosed
US-7112431-B2 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO. INC. (JP) 2006-09-26 US disclosed
US-20050084946-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2005-04-21 US disclosed
US-6815195-B2 NUCLEOTIDE SEQUENCES CODING PREFERENTIAL PROTEIN FOR USE IN GENERATING RACEMIC AMINO ACIDS AJINOMOTO CO. INC. (JP) 2004-11-09 US disclosed
US-20020102713-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2002-08-01 US disclosed
EP-1188826-A2 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids Ajinomoto Co., Inc. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050084946-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids HDHD5, HAAO, MTAP PTGER3 4018/4885BRD4 4820/4885LMNA 2166/4885
US-20020102713-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids HDHD5, HAAO, MTAP PTGER3 4018/4885BRD4 4820/4885LMNA 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.