Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435330 | 0.90 | MAOB (0.49) | MAOBJUNNFKB1FDPSTTR | |
| SCHEMBL29136859 | 0.85 | JUN (0.53) | JUNNFKB1TDP1DPP4CYP1A2 | |
| SCHEMBL29302359 | 0.85 | JUN (0.53) | JUNNFKB1TDP1DPP4CYP1A2 | |
| SCHEMBL12652769 | 0.85 | FBP1 (0.47) | FBP1FDPSTTRDPP4CA12 | |
| SCHEMBL2135232 | 0.83 | MAOB (0.48) | MAOBJUNNFKB1FBP1FDPS | |
| SCHEMBL1562282 | 0.83 | MAOB (0.48) | MAOBFDPSTTRDPP4CA12 | |
| SCHEMBL16318865 | 0.83 | MAOB (0.48) | MAOBJUNNFKB1FBP1FDPS | |
| SCHEMBL1562279 | 0.83 | MAOB (0.48) | MAOBFDPSTTRDPP4CA12 | |
| SCHEMBL29843895 | 0.83 | TTR (0.48) | MAOBFBP1FDPSTTRDPP4 | |
| SCHEMBL12652748 | 0.83 | CA12 (0.59) | MAOBTTRDPP4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |