Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15602073 | 0.91 | RAB9A (0.44) | HSD17B10MTNR1AMTNR1BFFAR1ADRA1A | |
| SCHEMBL1891972 | 0.91 | POLB (0.50) | HSD17B10MTNR1AMTNR1BFFAR1POLB | |
| SCHEMBL38659657 | 0.91 | POLB (0.50) | HSD17B10MTNR1AMTNR1BFFAR1POLB | |
| SCHEMBL1890644 | 0.87 | MTNR1A (0.42) | HSD17B10MTNR1AMTNR1BFFAR1TSHR | |
| SCHEMBL38659061 | 0.87 | MTNR1A (0.42) | HSD17B10MTNR1AMTNR1BFFAR1TSHR | |
| SCHEMBL19257272 | 0.83 | POLB (0.50) | HSD17B10FFAR1POLBLMNAMAPT | |
| SCHEMBL15602007 | 0.82 | POLB (0.46) | HSD17B10FFAR1POLB | |
| SCHEMBL12660792 | 0.81 | POLB (0.52) | HSD17B10MTNR1AMTNR1BFFAR1PKM | |
| SCHEMBL19257560 | 0.80 | POLB (0.46) | HSD17B10FFAR1POLBMAPT | |
| SCHEMBL19209443 | 0.79 | S1PR1 (0.51) | HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |